Toxicology Report Review demo
Reads every CRO toxicology report, checks it against its own tables, and lays the program out as one target-organ map with the exposure margin for each organ at the clinical dose. 1:14
What the demo shows
A toxicology review solution for safety scientists that pulls NOAELs from CRO reports.
Six agents read each CRO report as it arrives, extract findings by organ, incidence, severity, NOAEL and TK exposure with the page for every value, compute exposure margins against the clinical dose and check the summary against the tables, the protocol and the rest of the program. The toxicologist works from one target-organ map whose margins recalculate when the clinical dose changes, decides each issue and signs.
Transcript
- Toxicology Report Review checks every CRO toxicology report for the sponsor's safety scientists.
- By hand, one 400-page draft takes nearly three days.
- Organs run down the side, studies across, each finding cited to its page.
- Each row ends in that organ's margin at today's dose.
- Liver, 5.1 times.
- The team wants 400mg.
- One click, the liver falls to 2.4 and its row turns red.
- The highest dose keeping every adverse organ above 5 times, about 205mg.
- In the rat draft, the checker found six discrepancies, one quoting day, one exposure.
- She sends all six to the CRO and signs in hours, not days.
- Built on Botminds: agents, data, screens, and governance on one platform.
Transcribed from the film’s narration. Captions are on the player.