Target Safety Assessment demo
A body map of one target's on-target risks, organ by organ, from knockout mice, human carriers, expression and same-mechanism drugs, scored, cited and signed by a toxicologist. 1:15
What the demo shows
A nonclinical safety solution for toxicologists that reports a target's on-target risks, cited.
Type a target and five evidence agents read genetics, knockout phenotypes, expression, same-mechanism drugs, pathway and the company's own studies in parallel. Organs light on a body map as findings land, each with a badge showing whether the knockout mouse and people with a broken copy agree, disagree, or one is missing. A risk scorer proposes probability × impact, a critic challenges weak evidence, and the toxicologist re-scores with a reason and signs.
Transcript
- Target Safety Assessment shows toxicologists where a new drug target could hurt, organ by organ, every risk cited.
- By hand, one assessment takes two weeks of reading genetics, knockout mice and drug labels.
- Each organ shows whether the knockout mouse and people with a broken copy agree.
- Lena types a new target, an L or P15.
- Six agents read in parallel and light the organs.
- The heart turns amber.
- Knock out my show, a longer cutie, but carriers of a broken copy do not.
- That disagreement becomes the question, and a dog telemetry study goes into the plan.
- She checks the sighted source passage and signs the assessment.
- A sighted safety assessment for any new target in under two days, not two weeks.
- Build on Botminds, agents, data, screens, and governance on one platform.
Transcribed from the film’s narration. Captions are on the player.