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Research Conflict of Interest & Research Security Review

Research conflict of interest review that reads the public record, asks the investigator first, and cites every item

Undisclosed ties found before just-in-time, and explained by the researcher first.

See one case, screen by screen ↓
demo17key peoplein just-in-time checked against the public record overnight on the sample day; 16 fully matched, 1 with items not yet matched
demo0itemslabeled a violation by an agent this year in the working solution; what nothing covers is "Not yet matched"
target100%of senior and key people checked against the public record before just-in-time
target2daysmedian from the question to the recorded answer for an unmatched item
In short

What is Research Conflict of Interest & Research Security Review?

It is research conflict of interest and research security review for COI offices: agents read each senior and key person's papers, patents, talks and public profiles and tie every item to the disclosure, other support line, appointment or management plan that covers it. What nothing covers is "Not yet matched", never a violation, and the investigator is asked one neutral question before anything is recorded. The COI analyst, the Director, the research security officer and the signing official decide and sign.

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Updated

The problem

Why research conflict of interest review misses what the papers say

Research conflict of interest review today compares forms with forms. An investigator's annual disclosure, their NIH other support and their HR appointment record can agree perfectly while one of their own papers lists a second affiliation and thanks another institution for a visiting appointment, facility access and travel. That gap, between what was disclosed and what the public record shows, is what the federal foreign-support cases turned on, and since January 25, 2026 every NIH Common Form carries a personal certification of no participation in a malign foreign talent recruitment program.

Nobody has time to read the public record. A COI analyst cannot read 31 papers, 2 patents and 14 talks for every senior and key person in NIH just-in-time, so the check runs only after a tip or a sponsor letter, and a check triggered by a name or a nationality is unfair. Discrepancies are emailed back and forth while the PHS clocks run: 30 days to disclose a new interest, 60 days to report a financial conflict of interest, 120 days for a retrospective review. Research Conflict of Interest & Research Security Review gives every key person the same check, on documented facts, and lets the investigator explain before anything is recorded.

typical$1.9Mpaid by one university in 2023 to resolve allegations that it omitted foreign support for 12 faculty from proposals to five federal agencies
typical$5.5Mpaid by one research institute in 2019 over foreign grants not disclosed on NIH applications
demo47itemsin one investigator's public record on the sample day (31 publications, 2 patents and 14 talks), too many to read by hand for every key person
Where one investigator's review days go, in working daysestimated
By hand14 days
With the solution2.3 days
  • Searching publication, patent and conference databases by hand1 → 0.1 d
  • Comparing what was found with the disclosure, other support and HR record1 → 0.1 d
  • Writing the question and having it checked1 → 0.1 d
  • Waiting for and chasing the investigator's answer6 → 1.5 d
  • Checking the answer, recording the outcome and a second review2 → 0.2 d
  • Correcting other support and the disclosure, certified and signed3 → 0.3 d

Estimated working days for one investigator whose public record shows something nothing on file covers, by hand and with the agents. The 'after' rows from the question to the recorded answer stay within the 2-day target median; the rest is our arithmetic, kept modest.

How it works

How a just-in-time check moves

Seven agents read the public record, tether it to what was disclosed and ask the investigator; people decide and sign.

What comes in
Records in6 sources a person · disclosures, other support, papers, patents, talks, travel
Agents at work
Fairness guarddocumented facts only
Then
Footprint agentpapers, patents, talks
Matcher agenttethers + confidence
Then
Clarification agentone neutral question
Then
Support update agentcorrected other support
Plan and reporting agentplans, reports, binder
A person decides
COI analyst and Directorrecord and confirm
What comes out
Answer on the record
Other support signed
Certification ready
One case, step by step

One investigator, through research conflict of interest review to corrected other support

Dr. Tobias Okonjo-Reyes, Associate Professor of Biomedical Engineering at Halden State University, is in NIH just-in-time for his R01 application SP-27-0044, with other support due Friday, October 30, 2026. Here is his review, screen by screen, in the working solution.

  1. 01Tuesday, 11:40 p.m.

    Every key person in just-in-time gets the same check overnight

    Footprint agent

    Before any agent read a record, the Fairness guard removed a place-of-birth line on one public profile and a citizenship field in the HR feed. The Footprint agent then read his publications, patents, talks, public profiles, trips and HR appointment overnight. One conference site timed out, so the Talks source shows 13 of 14 read with a Retry button; a gap is never silent.

    28 items tied at 0.95 or more and 3 not yet matched; handed to Mira Sandoval with one question drafted.

  2. 02Wednesday morning

    Her day starts with what needs her, ordered by clock

    Mira Sandoval · COI Analyst

    Today shows four numbers: 2,846 of 3,100 annual disclosures certified, 46 open reviews (27 hers), 1,046 key people checked for just-in-time this year and 3 clocks at risk. "Needs you" is led by Dr. Okonjo-Reyes: 3 items not yet matched, one question ready.

  3. 03One click

    Disclosed and found, joined line by line

    Matcher agent

    On the left, 8 records he disclosed or that are on file, from his 2026 annual disclosure to management plan MP-24-031. On the right, 9 of 31 public-record items. Six are tied to the record that covers them with the Matcher's confidence, 0.95 to 0.99; three are not.

    Not yet matched · 1 question for the investigator

  4. 04The source

    The passage behind a found item, highlighted

    Mira Sandoval

    She opens the April 2025 paper in Hydrogel Science Letters: page 1, footnote 2 names a second affiliation at the Laboratory for Soft Materials, Varnholm University, and page 14 thanks it for a visiting appointment, rheometry facility access and travel support. She asks whether anything on file mentions Varnholm University; the cited answer is no, from his annual disclosure, R21 other support, HR record and the travel system.

  5. 059:05 a.m.

    One neutral question, checked before it is sent

    Clarification agent · Dr. Gideon Achterberg, Director

    The agent grouped the paper, the lab's web page and a March 2024 seminar into one question, CL-26-0193, each item cited, asking what the appointment involved, its dates and any pay, resources or travel support. Mira sent it for the Director's check at 9:05 a.m.; he approved it and it went out at 9:12 a.m., due Wednesday, October 28.

    No "violation", "undisclosed" or "foreign"; every item cited; due before the October 30 deadline.

  6. 0610:41 a.m.

    He explains first, and the answer is checked against the sources

    Dr. Tobias Okonjo-Reyes · Investigator

    He attaches the appointment letter, the closing email and two travel reimbursements. The Clarification agent checks each point with a citation: the dates agree (0.96), no remuneration or equity (0.94), $930 and $1,380 of travel paid by a foreign university to disclose (0.97), and other support to correct for the 10-month overlap with his R21 (0.95).

    "This was an unpaid visiting appointment from January 2023 to June 2024. … I have no continuing role."

  7. 0711:02 a.m.

    The outcome, with a reason code and a second person

    Mira Sandoval · Dr. Gideon Achterberg

    Mira records E2, explained, records to update, with a note: unpaid appointment confirmed by the letter and closing email, no remuneration or equity, two trips to add, other support to correct, no FCOI. The Director confirms at 11:06 a.m., and the item goes to research security.

  8. 0811:18 a.m.

    Research security decides on documented facts

    Colette Marchetti · Research Security Officer

    She sees the appointment's documented facts: unpaid, January 15, 2023 to June 30, 2024, ended, $2,310 in travel. Each of the six talent-program features reads "Not present", and a note confirms name, nationality, citizenship and birthplace were removed. She records S1: not a malign foreign talent recruitment program.

  9. 092:38 p.m.

    His disclosure update, prefilled from his own answer

    Dr. Tobias Okonjo-Reyes

    In his portal the Disclosure agent proposes the two trips, October 9–20, 2023 ($930) and March 4–15, 2024 ($1,380), with the travel rule explained and cited. He confirms both and certifies; his portal also answers whether this will be reported to NIH as a conflict: it will not.

  10. 103:05 p.m.

    Corrected other support, certified and signed, 9 days early

    Karen Ostrowski · Authorized organization representative

    The Support update agent added three cited lines to his Common Form other support: the unpaid visiting appointment, about 6 weeks of facility access and $2,310 in travel support. He certified at 2:40 p.m.; Karen signed and submitted at 3:05 p.m., 9 days before the deadline.

    What is not changed: no FCOI report, no "violation" anywhere, plan MP-24-031 unchanged.

Who it’s for

Built for everyone who signs a disclosure, a question or a submission.

The same review, seen by the people who carry it: what their day looked like, and what it looks like now.

MS
Mira SandovalCOI analyst · 27 open reviews
COI Analyst
Before
Compares disclosures with other support and HR records, and searches the public record by hand only after a tip arrives.
Now
Starts the day with every key person in just-in-time already checked, the gaps tied to their sources and one question drafted.
GA
Dr. Gideon AchterbergDirector · checks every question and outcome
Director of Research Integrity and Conflict of Interest
Before
Owns the agency reports while discrepancies are emailed back and forth and the answers live in an inbox.
Now
Approves every question before it is sent and confirms every outcome, with the cited items, the answer and the checks on one screen.
CM
Colette MarchettiResearch security officer · foreign appointments, travel, training
Research Security Officer
Before
Decides foreign-appointment questions that arrive without the documents behind them.
Now
Decides on documented facts only, against the six talent-program features, and sees what the Fairness guard removed.
TO
Dr. Tobias Okonjo-ReyesAssociate Professor of Biomedical Engineering · NIH R01 in just-in-time
Investigator
Before
Did not know an unpaid visiting appointment counted as other support.
Now
Answers one neutral question in his own words, confirms two trips the agent prefilled, and certifies.
AS
Dr. Anand SeshadriVice President for Research · signs FCOI reports and the certification
Vice President for Research
Before
Must certify a research security program whose training, travel, cybersecurity and export control evidence sits in different offices.
Now
Certifies from one binder of 26 items across four program elements, each linked to its evidence.
Built on the engine

7 agents. Each with one job, and hard limits.

Seven agents read the public record, tether it to what was disclosed and ask the investigator; people decide and sign.

Disclosure agent

Guides annual and ad hoc disclosures in plain questions, explains each threshold in a sentence, and prefills from HR, travel and the investigator's own answers.

  • Never certifies for the investigator
  • Never decides whether an interest is significant
Footprint agent

Reads a person's publications (affiliations and funding acknowledgments), patents, talks, public profiles and travel records.

  • Never reads private accounts or social media
  • Never uses a name, nationality, citizenship or birthplace
Matcher agent

Ties each found item to the disclosure, other support line, appointment, invention disclosure or management plan that covers it, with a confidence and a citation at both ends.

  • Never labels an item a violation
  • From 0.70 to 0.89 asks the analyst; below 0.70 the item stays "Not yet matched"
Fairness guard

Removes name origin, nationality, citizenship, place of birth, ethnicity and language from every agent's input, logs what it removed, and blocks any statement that rests on them.

  • Cannot be switched off by any role
  • Never edits evidence
Clarification agent

Groups unmatched items by topic, drafts one neutral question, then checks the investigator's answer against the sources and the rules.

  • Never sends without the Director's check
  • Never suggests an outcome to the investigator
Support update agent

Drafts the corrected Common Form other support and the disclosure update, line by line, with each source cited.

  • Never submits
  • The investigator certifies and the authorized organization representative signs
Plan and reporting agent

Drafts management plans from like plans, FCOI reports and annual reports, and keeps the research security certification binder current.

  • Never files with an agency
  • The Vice President for Research signs
Analyst, Director, research security officer

Decide, confirm and sign. The agents propose; a named person decides.

Ask in plain words

Ask about any investigator, item or clock

Ask about any investigator, item, clock or report, or say what to prepare. Every answer cites its source.

Why is the Varnholm affiliation not yet matched?

Nothing on file covers it. His April 2025 paper lists the Laboratory for Soft Materials, Varnholm University, as a second affiliation and thanks it for a visiting appointment, facility access and travel support. His annual disclosure, R21 other support and HR record list no outside appointment. It is grouped with the lab's web page and the March 2024 seminar into one question. It is not a finding: he explains first.

Which clocks are at risk this week?

Three: Dr. Okonjo-Reyes's just-in-time other support is due Oct 30; Dr. Beatriz Nwosu's review is on day 41 of 60; Dr. Imani Rutherford's annual disclosure is 21 days overdue after two reminders.

Draft the corrected other support for Dr. Okonjo-Reyes

The corrected lines come from his recorded answer: the unpaid visiting appointment, the in-kind facility access and $2,310 in travel support, with the R21 overlap. Unpaid appointments count. He certifies, then Karen Ostrowski signs.

Show the research security certification evidence

The binder has 26 items across the four program elements; 24 are ready. Training is current for 1,201 of 1,284 people. Two items are missing: one college's cybersecurity attestation and an export control roster. The Vice President for Research certifies when all 26 are ready.

Every screen

The working solution, as it ships.

13 screens from the working solution, on its sample data. Pick one to see it large.

Disclosed and found, side by sideDr. Tobias Okonjo-Reyes, in NIH just-in-time for R01 SP-27-0044. On the left, 8 records he disclosed or that are on file: his 2026 conflict of interest disclosure (Ardent Polymer Labs consulting, $12,500; Brightwell Biomaterials advisory board, $3,000), a May 2026 keynote travel disclosure ($1,840), NIH R21 and NSF current and pending support, an invention disclosure, management plan MP-24-031 and his HR appointment. On the right, 9 of 31 public-record items: six tied to a record with the Matcher's confidence (0.95 to 0.99), and three under "Not yet matched": an April 2025 paper with a second affiliation at the Laboratory for Soft Materials, Varnholm University, the lab's web page listing him as Visiting Professor 2023–2024, and a March 12, 2024 seminar.
The COI analyst's dayMira Sandoval's Today screen: 2,846 of 3,100 annual disclosures certified, 46 open reviews (27 hers), 1,046 key people checked for just-in-time this year, 3 clocks at risk. "Needs you" lists five items by clock, led by Dr. Okonjo-Reyes. The overnight sweep checked 17 key people: 16 fully matched, 1 with items not yet matched. The PHS clocks sit beside them: 30-day new interests, 60-day FCOI reports and 120-day retrospective reviews.
The source passage behind a found itemThe April 2025 paper in Hydrogel Science Letters, opened from the comparison: page 1, footnote 2 highlights "Laboratory for Soft Materials, Varnholm University" as a second affiliation; page 14 highlights the acknowledgment of "a visiting appointment, access to its rheometry facility and travel support". The analyst asks whether anything on file mentions Varnholm University, and the cited answer names his annual disclosure, R21 other support, HR record and travel system.
The Footprint and Matcher agents at workThe agents' plan, step by step: one senior/key person, six sources, confidence threshold 0.90; the Fairness guard removing a place-of-birth line and a citizenship field; 31 publications and 2 patents read; one conference site timing out (13 of 14 talks read, with a Retry button); 28 items tied at 0.95 or more and 3 not yet matched; the hand-off to Mira Sandoval with one question drafted.
One neutral question, checked before it is sentQuestion CL-26-0193 to Dr. Okonjo-Reyes, drafted by the Clarification agent: the three items in plain words, each cited, asking what the appointment involved, its dates and any pay, resources or travel support, due Wednesday, October 28. Maker Mira Sandoval sent it for check at 9:05 a.m.; checker Dr. Gideon Achterberg, the Director, can approve and send it or return it with a reason.
His answer, checked against the sourcesDr. Okonjo-Reyes answered at 10:41 a.m.: an unpaid visiting appointment from January 2023 to June 30, 2024, about six weeks of rheometer use, travel paid twice ($2,310), no continuing role, with the appointment letter, the closing email and two reimbursements attached. The Clarification agent's checks are each cited with a confidence, and the outcome takes a reason code from E1–E3 or R1–R2, with E2 proposed and a note required.
The outcome, confirmed by the DirectorDr. Gideon Achterberg confirms outcome E2, explained, records to update, recorded by Mira Sandoval at 11:02 a.m. with her note: no remuneration or equity, two trips to add, other support to correct, no financial conflict of interest. He can return it to the analyst or confirm it as Director.
Research security decides on documented factsColette Marchetti's research security review: the foreign appointment's documented facts, the six talent-program features each "Not present", and her decision S1, not a malign foreign talent recruitment program, at 11:18 a.m. Beside it, research security training (1,201 of 1,284 current; 83 due in 30 days; 19 expired), 27 of 27 trips briefed, and the Fairness guard this month: 41 inputs removed, 0 statements blocked.
Corrected other support, certified and signedThe Common Form current and pending (other) support for Dr. Okonjo-Reyes, with the R21 and NSF lines unchanged and three cited lines added: the unpaid visiting appointment, facility access for about 6 weeks and $2,310 in travel support. Prepared by Mira Sandoval at 11:20 a.m., certified by the investigator at 2:40 p.m., signed and submitted by Karen Ostrowski at 3:05 p.m., 9 days before the NIH just-in-time deadline.
What the investigator seesDr. Okonjo-Reyes's portal: the Disclosure agent prepared his update from his answer, two trips to confirm (October 9–20, 2023, $930; March 4–15, 2024, $1,380), both confirmed and certified at 2:38 p.m., with the travel rule explained and cited. "Ask about your disclosure" answers whether an unpaid appointment counts and whether this will be reported to NIH as a conflict.
The research security program, ready to certifyThe research security program certification for an institution with over $50 million a year in federal R&D: four elements (research security training, foreign travel security, cybersecurity and export control training) and an evidence binder of 26 items, each linked to its evidence, prepared by Colette Marchetti and certified by Dr. Anand Seshadri, Vice President for Research.
Results and agency reportsFiscal year 2026–27 to date: 1,046 of 1,046 key people checked before just-in-time; a 2-day median from question to recorded answer (84 investigators asked, 77 resolved); 37 of 37 FCOI reports filed within 60 days; 0 items labeled a violation by an agent. Below, each agency report with its clock and the Vice President for Research's signature.
The audit trail and its export packEvery action on Dr. Okonjo-Reyes's review by people and agents, with when, who, what, why (a reason code or a role: maker, checker, certifier, signer) and the cited evidence. The export pack offers NIH, NSF, inspector general and research security certification packs, redacts people outside the request, and is sealed with a fingerprint.
Governance

Research security review you can defend: fair, cited, signed.

Nine roles, separated by dutyCOI analyst, Director, committee chair and members, research security officer, authorized organization representative, Vice President for Research, investigator, administrator and auditor. An analyst cannot check their own work, the research security officer cannot record COI outcomes, and the administrator never sees review contents.
Maker-checker on every decisionThe analyst drafts a question and the Director checks it; the analyst records an outcome and the Director confirms it; the committee votes and the Chair signs a plan; the investigator certifies other support and the authorized organization representative signs; the Vice President for Research signs FCOI reports and the certification.
A Fairness guard that is locked onName origin, nationality, citizenship, place of birth, ethnicity and language never reach an agent, and no statement may rest on them. The agents use documented facts only: appointments, payments, affiliations, acknowledgments, contracts, travel and dates.
Versioned agents, overrides with a reasonEach agent has a version, a prompt version, a model, a confidence threshold and its last evaluation score; any change is a new version the Director approves. An analyst who changes a tie picks a reason code, M1 to M4 or T1 to T3, and every override is reviewed monthly.
Privacy, retention and redaction by ruleReview records are kept 3 years from the final expenditure report. Auditors see initials only, public requests for FCOI information get the required fields within 5 business days, and for enrolled student investigators only research disclosures are read, never education records.
Every step cited, on a trail you can exportEvery action by people and agents records when, who, what, why and the cited evidence. Export packs for NIH, NSF, an inspector general and the research security certification redact people outside the request and carry a fingerprint.
Configuration

Your COI policy and clocks, not ours

The thresholds and clocks every review runs on are settings, versioned, and changed only with the Director's approval.

SettingDefaultChoose from
Significant financial interest threshold$5,000PHS rule; the institution may set it lower
Sponsored or reimbursed travelEvery tripExcept travel paid by US universities and governments
Just-in-time footprintEvery senior/key personCannot be limited to some people
Matcher confidenceTies on its own at 0.90 and above0.70–0.89 asks the analyst; below 0.70 stays not yet matched
Reply to a question5 business daysThen 2 reminders, then the department chair
FCOI report to the agency · retrospective review60 days · 120 daysClock warnings 5 days and 1 day before; escalations to the Director
Fairness guardLocked onName origin, nationality, citizenship, place of birth, ethnicity and language removed
Review records3 years from the final expenditure report42 CFR 50.604(i); auditors see initials only
Connections

Works with the systems a research office already runs on

COI disclosure systemdisclosures, management plans and questions
Research administration systemproposals, awards, other support and just-in-time requests
HR systemappointments
Publication and patent databasespapers, affiliations, acknowledgments, applications and grants
Travel systemtrips and reimbursements
Agency grants portaljust-in-time packages and FCOI reports
What it changes

The difference, in numbers.

Every figure is labelled: a target the solution is built to, an estimate, a typical published result, or a proven one.

target
100%
of key people checked against the public record before just-in-time
Every key person
before the sponsor sees it
typical
60days
FCOI report clock tracked and escalated on every conflict
target
2days
from question to recorded answer for an unmatched item

"demo" = seen in the working solution, on its sample data · "target" = design goal, measured in the live solution · "estimated" = our arithmetic, kept modest (the days split) · "typical" = published figures: US Department of Justice, October 2, 2023 ($1.9 million, foreign support omitted for 12 faculty from proposals to five federal agencies); HHS Office of Inspector General, 2019 ($5.5 million, foreign grants not disclosed on NIH applications). Rules named as context: 42 CFR Part 50 Subpart F; NIH NOT-OD-21-073 and the Common Forms, NOT-OD-26-018; CHIPS and Science Act §§10631–10638; NSPM-33 and the OSTP research security program guidelines of July 9, 2024; FERPA, 34 CFR Part 99. Halden State University, Varnholm University, the companies, journal and society, and the people named on this page are fictional — characters and sample data in the working solution.

Questions

What COI offices ask about research conflict of interest review.

What is Research Conflict of Interest & Research Security Review?

It is research conflict of interest and research security review for COI offices: agents read each senior and key person's papers, patents, talks and public profiles and tie every item to the disclosure, other support line, appointment or management plan that covers it. What nothing covers is "Not yet matched", never a violation, and the investigator is asked one neutral question before anything is recorded. The COI analyst, the Director, the research security officer and the signing official decide and sign.

What is a financial conflict of interest in research?

Under the PHS rule, 42 CFR Part 50 Subpart F, an investigator discloses significant financial interests above $5,000, and the institution decides whether an interest is related to the research and could bias it. A related interest that is a financial conflict of interest gets a management plan, approved by the COI committee, and is reported to the PHS awarding component within 60 days. In the solution the analyst and Director work the review, the committee votes and the Chair signs the plan.

Does an unpaid foreign appointment have to be listed in NIH other support?

NIH's other support instructions cover all resources in support of an investigator's research, including in-kind resources and foreign appointments, whether paid or unpaid. In the sample review, an unpaid visiting appointment that a 2025 paper revealed was added to the corrected R21 other support with its facility access and travel support, certified by the investigator and signed by the authorized organization representative.

How does it fit the NIH just-in-time deadline?

Every senior and key person in NIH just-in-time gets the same footprint check, and the deadline is tracked to the day. In the sample review, the request arrived October 8, the question went out October 21 at 9:12 a.m., and the corrected other support was submitted that afternoon, 9 days before the October 30 deadline.

Does it help with the research security program requirements under NSPM-33?

Institutions with more than $50 million a year in federal R&D must certify a research security program covering cybersecurity, foreign travel security, research security training and export control training. The solution keeps the evidence in one binder, each item linked to its source: training within 12 months, travel briefings, foreign-appointment decisions and footprint checks. The research security officer prepares it and the Vice President for Research certifies.

Does it single out researchers by name or nationality?

No. A Fairness guard removes name origin, nationality, citizenship, place of birth, ethnicity and language before any agent reads a record, shows what it removed, and cannot be switched off. Every key person gets the same check on documented facts: appointments, payments, affiliations, acknowledgments, contracts, travel and dates.

Do people stay in control of the decision?

Yes. Agents never label anything a violation, never contact an investigator without a question the Director has checked, and never submit anything to an agency. The analyst records each outcome with a reason code and the Director confirms it; the research security officer decides talent-program questions; the investigator certifies and the authorized organization representative signs.

How long does it take to go live?

The Agentic Solution Engine builds and deploys it from your requirements and documents, such as your COI policy, disclosure forms and a sample of past reviews, and it goes live once every quality gate has passed. We will walk you through it on your own key personnel first.

See it on
your key personnel.

We'll run Research Conflict of Interest & Research Security Review on a sample of your own disclosures, other support and public records.